Chemical and Biomolecular Analysis Facility
The Chemical and Biomolecular Analysis Facility offers services, expertise, and collaboration for the research community at Augusta
University, other academic institutions, and for-profit companies.
Our main instrumentation includes high field nuclear magnetic resonance (NMR), liquid chromatography–mass spectrometry (LC-MS), high-performance liquid chromatography (HPLC), circular dichroism spectrometer (CD), and inductively coupled plasma optical emission spectrometry (ICP-OES).
Electron Microscopy and Histology Core
The Electron Microscopy & Histology Core Laboratory is located in CB 1113 in the Carl Sanders Research and Education building.
The Core is supported by the Department of Cellular Biology and Anatomy and user fees.
The core is available to all Augusta University affiliated investigators and off-campus
Genomics & Proteomics Core Labs
The Proteomics Core Laboratory at Augusta University is a resource facility for the
characterization and expression level measurement of proteins (isolated or in an extract)
by mass spectrometry (MS), electrophoresis, or chromatography.
The Genomics Core Laboratory (GCL) at the Augusta University is a multi-functional
molecular biology resource facility.
Both labs are directed through the Center of Biotechnology and Genomic Medicine. Services
are available to all campus investigators, students and incubator tenants, as well
as off-campus users.
Georgia Cancer Center | Integrated Genomics and High Performance Computer (HPC) Server
The Integrated Genomics Shared Resource in the Georgia Cancer Center houses a complete Illumina NextGen Sequencing Facility including both HiSeq and MiSeq
instruments. Expertise for performing DNA-Seq, RNA-Seq, Chip-Seq, Methyl-Seq and targeted
re-sequencing is available. Microarray resources include Affymetrix ® and Agilent
® Scanner Platforms that facilitate exon-specific, oligonucleotide and genome-wide
arrays. Bioinformatic support is available for data analysis for both sequencing and
Georgia Cancer Center | Proteomics and Metabolomics Facility
Proteomics and Metabolomics, a part of system biology, is fundamental for a full understanding of a biological
system including a metabolic process or disease state, and has received considerable
attention since the sequencing of the human genome. Mass spectrometry based technologies
have been indispensable to the development of molecular medicine. Clinical research
can also benefit from proteomics and metabolomics by both the identification of new
drug targets and the development of new diagnostic markers.
- Offer state of the art proteomics and metabolomics service to Georgia Cancer Center
- Assist in the analysis of data resulting from investigations into the metabolome or
- Assist in the writing of grants or manuscripts involving proteomics or metabolomics
Georgia Cancer Center | Flow Cytometry Core Facility
The Flow Cytometry Core Facility is a shared resource providing access to flow cytometers, support equipment, and
associated software and services. Our instrumentation affords the ability to perform
almost every published flow cytometry protocol.
Georgia Cancer Center | Immune Monitoring Resource
The main objective of the core is to provide standardized immune-based assays, to
develop, optimize, and validate new technologies, and to support efforts in the areas
of human and animal immunology and immunotherapy.
The IMSR works closely with the Flow Cytometry Core, the Integrated Genomic Shared Resources,
and the Tumor Tissue and Serum Repository at the Georgia Cancer Center.
Georgia Cancer Center | Small Animal Imaging Resource
Small Animal Imaging has been commissioned to provide a wide range of imaging and radiation treatment
resource for animal research. The preclinical services are translational in operation
while remaining cutting edge in the advancement of basic research. The services are
available to the Augusta University Research Enterprise and other outside scientific
Georgia Cancer Center | Bioinformatics Shared Resource
The GCC Bioinformatics Shared Resource provides expertise in integrative computational-based analysis solutions to basic,
clinical, and translational research applications. Bioinformatics support ranges in
scope from simple consultations to more in-depth collaborations. We require the participation
of the investigator during the course of our data analysis because we believe that
input into the biological parameters are tantamount to success of the analysis.
Human Cord Blood Stem Cell Core
The Cell Imaging Core Laboratory provides expert technical assistance and instrumentation in support of investigators.
The Core also educates graduate students in the basic principles of imaging.
Small Animal Behavior Core
The Small Animal Behavior Core (SABC) is a state-of-the art facility designed to serve as a time-efficient and cost-effective
service for researchers in need of behavioral analyses in small animals (specifically,
mice and rats). The Core provides expertise in all aspects related to the design and
implementation of behavioral experiments as well as data analysis and interpretation.
The faculty and staff of the Georgia Esoteric and Molecular (GEM) Laboratory provide diagnostic services for the diagnosis and comprehensive evaluation of disease
primarily through the molecular analysis of tissues and cells. The faculty is comprised
of pathologists and doctoral scientists.
The mission of the GEM Lab is aligned with that of the Institution in its three focus
areas i.e. Patient care, Education, and Translational Research.
The GEM lab provides services under three groups:
- Clinical diagnostics and patient care via molecular diagnostic testing.
- Education: medical student, resident and fellow rotations, and medical technology
student clinical internship.
- Translational Research: research support and services to faculty at AU campus; research
support and services to clinical trials at AU.
Transgenic & Genome Editing Core
The Transgenic and Genome Editing Core is a full-service facility supported by Augusta University, The Georgia Research
Alliance, and user fees. The Core’s mission is to provide timely and cost-effective
services in all phases of transgenic mouse production by pronuclear microinjection
into zygotes, gene targeting in embryonic stem cells (ESCs), and gene editing using
CRISPR/Cas9 approach to the research community at Augusta University as well as other
academic institutions and for-profit companies. The Core also provides services on
preserving your valuable lines by cryopreservation of sperms and embryos, and resurrecting
mouse lines using in vitro fertilization (IVF) or embryo transfer. Additional services
include rederivation to create pathogen-free mouse lines, developing molecular reagents
for genetic engineering, full colony management services, and expert advice on mouse
genetics and breeding schemes. The Core is fully equipped to carry out the all procedures
of generating mouse models as well as related services.
Transgenic Zebrafish Core Laboratory
The Transgenic Zebrafish Core Laboratory functions to facilitate use of zebrafish as a vertebrate model system for basic and
biomedical science and comparative genomics. Services, equipment, and resources are
available to investigators associated with Augusta University or the University System
of Georgia on a fee-for-service basis.
Located in CA-3045 (Interdisciplinary Research Building), the Zebrafish Core Laboratory
is equipped to maintain ~50,000 adult fish (3000 aquaria) in a temperature and light-controlled
environment. A dedicated staff ensures continuity of care, breeding, and quality embryo
production. Core Laboratory microscopes, imaging equipment, and computers (see Instrumentation) are available for use by all Augusta University research laboratories.
Shared Research Services
Division of Laboratory Animal Services
The Division of Laboratory Animal Services maintains a centralized animal care program with administrative management of 6 on-campus
and 1 off-campus animal facilities. The animal care and use program is accredited
by AAALAC, a Registered Research Facility with the United States Department of Agriculture
(USDA No. 57-R-0002), and has an Office of Laboratory Animal Welfare Assurance number.
Research Support Center - Biostatistics
The mission of our biostatistics program is to advance knowledge in the fields of biostatistics, and to provide leadership
and scholarship in research, teaching and mentoring, for the advancement of biomedical
science and improvement of human health. We play a vital role in the education mission
and the multidisciplinary and translational research mission of Augusta University,
crossing the boundaries of academic colleges.
Central Supply Services (CSS) is a section of Research and Education Services in the Medical College of Georgia.
It is a campus facility providing sterilization, preparation and distribution of laboratory
supplies and materials.
Research Development Services
Research Development Services (RDS) provides support for obtaining approval for use of AU Medical Center, Clinics, Ancillary
Services, Medical Records, and Patients (recruited from or using these services) that
will be used during the conduct of a research study.
The Clinical Trials Office (CTO) serves as the initial point of contact and centralized coordinating office for all
clinical research conducted within Augusta University Health. Its mission is to facilitate
clinical research by providing quality services, solutions, innovative leadership,
the promotion of collaboration, and continuous quality improvement. Its operation
is based upon a comprehensive "One Stop Shop" concept for investigators and sponsors.
The clinical trials office provides oversight and management of clinical studies.
Laboratory Equipment Services (LES) is a Section of Research and Education Services in the Medical College of Georgia.
It is an on-site facility providing quality, low cost laboratory equipment repair,
preventive maintenance and biological safety cabinet certifications by certified technicians.
Institutional Review Board (IRB)
The Institutional Review Board (IRB) makes certain the research goals of the enterprise are met ensuring compliance and
protection of human subjects involved in research. To serve as the central contact
for facilitating the goals of the Enterprise Human Research Protection Program (HRPP).
Clinical Research Pharmacy
The AU Medical Center pharmacy has been assigned responsibility for study medication receipt, storage, dispensing,
accountability and record-keeping for all human subject research on campus.