Chemistry research is wide-ranging, with an emphasis on biomolecular compounds and drug discovery.

Undergraduate research in chemistry is a great way to get first-hand, real-life experience in a lab setting. The College of Science and Mathematics provides students access to the Chemical and Biomolecular Analysis Facility, a core resource with state-of-the-art instrumentation, including NMR, ICP, CD, and XRD spectroscopy, among others.

Contact Us

Department of Chemistry

Health Sciences Campus

Science & Mathematics Building

706-729-2259

chemistry@augusta.edu

Fundamental Backbone

Research Areas

Contact faculty member for more information on specific research areas.

The Borgini Lab

The Borgini Lab has deep expertise in the synthesis of peptides and small molecules for therapeutic applications. 

Research Interests: Chemical Biology / Medicinal Chemistry / Organic Chemistry / 

https://www.augusta.edu/scimath/chemistry/borgini-research-page.php 

The Culha Lab

The Culha Lab focuses on the implementation of the nanomedicine and nanobiotechnology concepts for the solution of today’s challenging problems such as cancer detection and treatment.

Research Interests: Materials Science 

https://www.augusta.edu/scimath/chemistry/culha-research-page-.php 

The Mori Lab

The Mori lab focuses on the characterization of natural product biosynthesis and the engineering of their biosynthetic enzymes to develop enzymatic tools. 

Research Interests: Natural Product Chemistry

https://www.augusta.edu/scimath/chemistry/mori-research-page.php 

The Verbeck Lab

The Verbeck Lab offers a suite of mass spectrometry and imaging instruments with applications in chemistry, biochemistry, toxicology, environmental, forensic, and material science.

Research Interests: Biochemistry / Environmental Chemistry / Forensic Chemistry / Materials Science / Toxicology /

https://www.augusta.edu/scimath/chemistry/verbeck-research-page.php 

Creativity, Discovery, Engagement

Publications

Publication

A spin–rotation mechanism of Einstein–de Haas effect based on a ferromagnetic disk

Nie, X., Li, J., Datta, T. & Yao, D. X., Oct 2024, In: Frontiers of Physics. 19, 5, 53201.

Research output: Contribution to journalArticlepeer-review

Periodicity staircase in a centrosymmetric Fe/Gd magnetic thin film system

Singh, A., Li, J., Montoya, S. A., Morley, S., Fischer, P., Kevan, S. D., Fullerton, E. E., Yao, D. X., Datta, T. & Roy, S., Dec 2024, In: npj Quantum Materials. 9, 1, 2.

Research output: Contribution to journalArticlepeer-review

Spiroindole-containing compounds bearing phosphonate group of potential Mpro-SARS-CoV-2 inhibitory properties

Bekheit, M. S., Panda, S. S., Kariuki, B. M., Mahmoud, S. H., Mostafa, A. & Girgis, A. S., Oct 5 2023, In: European Journal of Medicinal Chemistry. 258, 115563.

Research output: Contribution to journalArticlepeer-review

Microwave-assisted synthesis of five-membered azaheterocyclic systems using nanocatalysts

Panda, S. S. & Hansen, D. W., Jan 1 2023, Nanoparticles in Green Organic Synthesis: Strategy towards Sustainability. Elsevier, p. 255-278 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

Girgis, A. S., Panda, S. S., Kariuki, B. M., Bekheit, M. S., Barghash, R. F. & Aboshouk, D. R., Sep 2023, In: Molecules. 28, 18, 6603.

Research output: Contribution to journalReview articlepeer-review

PREFACE

Panda, S. S., 2024, In: Mini-Reviews in Organic Chemistry. 21, 1, p. 2 1 p.

Research output: Contribution to journalEditorialpeer-review

Rhodium-Catalyzed Regioselective C3Ar Functionalization of Tyrosines with Maleimides and Its Late-Stage Peptide Exemplification

Kharat, N. D., Naharwal, S., Tank, D., Panda, S. S., Bajaj, K. & Sakhuja, R., Oct 27 2023, In: Organic Letters. 25, 42, p. 7673-7677 5 p.

Research output: Contribution to journalArticlepeer-review

Systematic Investigation of Cellular Response to Hydroxyl Group Orientation Differences on Gold Glyconanoparticles

Sarıçam, M., Ercan Ayra, M. & Culha, M., Nov 14 2023, In: ACS Omega. 8, 45, p. 42921-42935 15 p.

Research output: Contribution to journalArticlepeer-review

Advancing Efficiency and Stability of Lead, Tin, and Lead/Tin Perovskite Solar Cells: Strategies and Perspectives

Khadka, D. B., Shirai, Y., Yanagida, M., Ryan, J. W., Song, Z., Barker, B. G., Dhakal, T. P. & Miyano, K., Nov 2023, In: Solar RRL. 7, 21, 2300535.

Research output: Contribution to journalReview articlepeer-review

Molecular Hybridization of Alkaloids Using 1,2,3-Triazole-Based Click Chemistry

Buchanan, D., Pham, A. M., Singh, S. K. & Panda, S. S., Nov 2023, In: Molecules. 28, 22, 7593.

Research output: Contribution to journalReview articlepeer-review

Microwave-Assisted Synthesis of Tri-Substituted 1,3,5-Triazines from Metformin Using Benzotriazole Chemistry

Panda, S. S., Thomas, E. & Pham, A. M., Dec 2022, In: Reactions. 3, 4, p. 516-524 9 p.

Research output: Contribution to journalArticlepeer-review

Editorial: Advances in natural product chemistry: Yunnan University 100th anniversary

Chen, W., Dong, J. & Panda, S. S., 2023, In: Frontiers in Chemistry. 11, 1234211.

Research output: Contribution to journalEditorialpeer-review

Potential RNA-dependent RNA polymerase (RdRp) inhibitors as prospective drug candidates for SARS-CoV-2

Bekheit, M. S., Panda, S. S. & Girgis, A. S., Apr 5 2023, In: European Journal of Medicinal Chemistry. 252, 115292.

Research output: Contribution to journalReview articlepeer-review

Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)

Patwardhan, C. A., Kommalapati, V. K., Llbiyi, T., Singh, D., Alfa, E., Horuzsko, A., Korkaya, H., Panda, S., Reilly, C. A., Popik, V. & Chadli, A., Dec 2023, In: Scientific reports. 13, 1, 13790.

Research output: Contribution to journalArticlepeer-review

Discrimination of Receptor-Mediated Endocytosis by Surface-Enhanced Raman Scattering

Yilmaz, D. & Culha, M., May 24 2022, In: Langmuir. 38, 20, p. 6281-6294 14 p.

Research output: Contribution to journalArticlepeer-review

DNA Gyrase as a Target for Quinolones

Spencer, A. C. & Panda, S. S., Feb 2023, In: Biomedicines. 11, 2, 371.

Research output: Contribution to journalArticlepeer-review

Editorial: Current approaches in infectious disease drug discovery

Silva-Jr, F. P., Panda, S. S., Andrade, C. H. & Furnham, N., Nov 30 2022, In: Frontiers in Chemistry. 10, 1102402.

Research output: Contribution to journalEditorialpeer-review

PREFACE

Panda, S. S., Feb 2023, In: Mini-Reviews in Organic Chemistry. 20, 1, p. 2 1 p.

Research output: Contribution to journalEditorialpeer-review

Spirooxindole: A Versatile Biologically Active Heterocyclic Scaffold

Panda, S. S., Girgis, A. S., Aziz, M. N. & Bekheit, M. S., Jan 2023, In: Molecules. 28, 2, 618.

Research output: Contribution to journalReview articlepeer-review

New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation

Bokhtia, R. M., Panda, S. S., Girgis, A. S., Samir, N., Said, M. F., Abdelnaser, A., Nasr, S., Bekheit, M. S., Dawood, A. S., Sharma, H., Wade, M., Sharma, S. K. & Ghanim, A. M., Feb 2023, In: Molecules. 28, 4, 1945.

Research output: Contribution to journalArticlepeer-review

Bicyclic 6-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Four Extra Heteroatoms 2:2

Panda, S. S. & Carr, J. A., Jan 1 2021, Comprehensive Heterocyclic Chemistry IV. Elsevier, p. 297-304 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Azomethine Ylides—Versatile Synthons for Pyrrolidinyl-Heterocyclic Compounds

Panda, S. S., Aziz, M. N., Stawinski, J. & Girgis, A. S., Jan 2023, In: Molecules. 28, 2, 668.

Research output: Contribution to journalArticlepeer-review

Modified Curcumins as Potential Drug Candidates for Breast Cancer: An Overview

Flint, A. L., Hansen, D. W., Brown, L. V. D., Stewart, L. E., Ortiz, E. & Panda, S. S., Dec 2022, In: Molecules. 27, 24, 8891.

Research output: Contribution to journalReview articlepeer-review

Investigation of effects of transferrin-conjugated gold nanoparticles on hippocampal neuronal activity and anxiety behavior in mice

Yavuz, Y., Yesilay, G., Guvenc Tuna, B., Maharramov, A., Culha, M., Erdogan, C. S., Garip, G. A. & Yilmaz, B., Aug 2023, In: Molecular and Cellular Biochemistry. 478, 8, p. 1813-1824 12 p.

Research output: Contribution to journalArticlepeer-review

Ursolic Acid Analogs as Potential Therapeutics for Cancer

Panda, S. S., Thangaraju, M. & Lokeshwar, B. L., Dec 2022, In: Molecules. 27, 24, 8981.

Research output: Contribution to journalReview articlepeer-review

Novel Curcumin Mimics: Design, Synthesis, Biological Properties and Computational Studies of Piperidone-Piperazine Conjugates

Youssef, M. A., Panda, S. S., Aboshouk, D. R., Said, M. F., El Taweel, A., GabAllah, M., Fayad, W., Soliman, A. F., Mostafa, A., Fawzy, N. G. & Girgis, A. S., Aug 19 2022, In: ChemistrySelect. 7, 31, e202201406.

Research output: Contribution to journalArticlepeer-review

Synthesis of Potential Antiviral Agents for SARS-CoV-2 Using Molecular Hybridization Approach

Wyman, K. A., Girgis, A. S., Surapaneni, P. S., Moore, J. M., Abo Shama, N. M., Mahmoud, S. H., Mostafa, A., Barghash, R. F., Juan, Z., Dobaria, R. D., Almalki, A. J., Ibrahim, T. S. & Panda, S. S., Sep 2022, In: Molecules. 27, 18, 5923.

Research output: Contribution to journalArticlepeer-review

Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-SARS-CoV-2 properties

Fawazy, N. G., Panda, S. S., Mostafa, A., Kariuki, B. M., Bekheit, M. S., Moatasim, Y., Kutkat, O., Fayad, W., El-Manawaty, M. A., Soliman, A. A. F., El-Shiekh, R. A., Srour, A. M., Barghash, R. F. & Girgis, A. S., Dec 2022, In: Scientific reports. 12, 1, 13880.

Research output: Contribution to journalArticlepeer-review

Label-Free Surface Enhanced Raman Spectroscopy for Cancer Detection

Avci, E., Yilmaz, H., Sahiner, N., Tuna, B. G., Cicekdal, M. B., Eser, M., Basak, K., Altıntoprak, F., Zengin, I., Dogan, S. & Çulha, M., Oct 2022, In: Cancers. 14, 20, 5021.

Research output: Contribution to journalArticlepeer-review

Influence of Protein Size on Surface-Enhanced Raman Scattering (SERS) Spectra in Binary Protein Mixtures

Avci, E. & Culha, M., Aug 2014, In: Applied Spectroscopy. 68, 8, p. 890-899 10 p.

Research output: Contribution to journalArticlepeer-review

Development of a SERS based cancer diagnosis approach employing cryosectioned thyroid tissue samples on PDMS

Mert, S., Sancak, S., Aydın, H., Fersahoğlu, A. T., Somay, A., Özkan, F. & Çulha, M., Aug 2022, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 44, 102577.

Research output: Contribution to journalArticlepeer-review

Raman and surface-enhanced Raman scattering for biofilm characterization

Keleştemur, S., Avci, E. & çulha, M., Mar 1 2018, In: Chemosensors. 6, 1, 5.

Research output: Contribution to journalReview articlepeer-review

Characterization techniques of living cells encapsulated with nanomaterials

Çulha, M., 2014, In: RSC Smart Materials. 2014-January, 9, p. 80-97 18 p.

Research output: Contribution to journalArticlepeer-review

Surface-enhanced Raman scattering of proteins

Kahraman, M., Sur, I. & Culha, M., 2010, XXII International Conference on Raman Spectroscopy, ICORS 2010. p. 1055-1056 2 p. (AIP Conference Proceedings; vol. 1267).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanospectroscopy Nanospectroscopy

Çulha, M., Nov 1 2015, In: Analytical and bioanalytical chemistry. 407, 27, p. 8175-8176 2 p.

Research output: Contribution to journalEditorialpeer-review

Surface-Enhanced Raman Scattering for Label-Free Living Single Cell Analysis

Kuku, G., Altunbek, M. & Culha, M., Nov 7 2017, In: Analytical Chemistry. 89, 21, p. 11160-11166 7 p.

Research output: Contribution to journalArticlepeer-review

Exploiting urazole’s acidity for fabrication of hydrogels and ion-exchange materials

Hanay, S. B., Fallah, A., Senturk, E., Yetim, Z., Afghah, F., Yilmaz, H., Culha, M., Koc, B., Zarrabi, A. & Varma, R. S., Dec 2021, In: Gels. 7, 4, 261.

Research output: Contribution to journalArticlepeer-review

Effects of developmental exposure to silver in ionic and nanoparticle form: A study in rats

Charehsaz, M., Hougaard, K. S., Sipahi, H., Ekici, A. I. D., Kaspar, Ç., Culha, M., Bucurgat, Ü. Ü. & Aydin, A., 2016, In: DARU, Journal of Pharmaceutical Sciences. 24, 1, 24.

Research output: Contribution to journalArticlepeer-review

Characterization of Yeast Species Using Surface-Enhanced Raman Scattering

Sayin, I., Kahraman, M., Sahin, F., Yurdakul, D. & Culha, M., Nov 2009, In: Applied Spectroscopy. 63, 11, p. 1276-1282 7 p.

Research output: Contribution to journalArticlepeer-review

Surface-raman scattering for medical applications

Çulha, M., Aug 31 2012, Biomedical Nanosensors. Pan Stanford Publishing Pte. Ltd., p. 97-119 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Evaluation of newly synthesized and commercially available charged cyclomaltooligosaccharides (cyclodextrins) for capillary electrokinetic chromatography

Culha, M., Schell, F. M., Fox, S., Green, T., Betts, T. & Sepaniak, M. J., Jan 22 2004, In: Carbohydrate Research. 339, 2, p. 241-249 9 p.

Research output: Contribution to journalArticlepeer-review

Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies

Seliem, I. A., Panda, S. S., Girgis, A. S., Tran, Q. L., Said, M. F., Bekheit, M. S., Abdelnaser, A., Nasr, S., Fayad, W., Soliman, A. A. F., Sakhuja, R., Ibrahim, T. S., Abdel-Samii, Z. K. M. & Al-Mahmoudy, A. M. M., Jul 5 2022, In: ChemMedChem. 17, 13, e202200164.

Research output: Contribution to journalArticlepeer-review

Design, Synthesis, and Molecular Docking Studies of Curcumin Hybrid Conjugates as Potential Therapeutics for Breast Cancer

Panda, S. S., Tran, Q. L., Rajpurohit, P., Pillai, G. G., Thomas, S. J., Bridges, A. E., Capito, J. E., Thangaraju, M. & Lokeshwar, B. L., Apr 6 2022, In: Pharmaceuticals. 15, 4, 451.

Research output: Contribution to journalArticlepeer-review

Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates

Ghanim, A. M., Girgis, A. S., Kariuki, B. M., Samir, N., Said, M. F., Abdelnaser, A., Nasr, S., Bekheit, M. S., Abdelhameed, M. F., Almalki, A. J., Ibrahim, T. S. & Panda, S. S., Feb 2022, In: Bioorganic Chemistry. 119, 105557.

Research output: Contribution to journalArticlepeer-review

Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays

Curreli, F., Ahmed, S., Victor, S. M. B., Drelich, A., Panda, S. S., Altieri, A., Kurkin, A. V., Tseng, C. T. K., Hillyer, C. D. & Debnath, A. K., Jan 2022, In: Viruses. 14, 1, 69.

Research output: Contribution to journalArticlepeer-review

Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates

Bokhtia, R. M., Girgis, A. S., Ibrahim, T. S., Rasslan, F., Nossier, E. S., Barghash, R. F., Sakhuja, R., Abdel-Aal, E. H., Panda, S. S. & Al-Mahmoudy, A. M. M., Feb 2022, In: Pharmaceuticals. 15, 2, 191.

Research output: Contribution to journalArticlepeer-review

3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2

Girgis, A. S., Panda, S. S., Srour, A. M., Abdelnaser, A., Nasr, S., Moatasim, Y., Kutkat, O., El Taweel, A., Kandeil, A., Mostafa, A., Ali, M. A., Fawzy, N. G., Bekheit, M. S., Shalaby, E. S. M., Gigli, L., Fayad, W. & Soliman, A. A. F., Sep 2021, In: Bioorganic Chemistry. 114, 105131.

Research output: Contribution to journalArticlepeer-review

New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS-CoV-2

Seliem, I. A., Girgis, A. S., Moatasim, Y., Kandeil, A., Mostafa, A., Ali, M. A., Bekheit, M. S. & Panda, S. S., Nov 19 2021, In: ChemMedChem. 16, 22, p. 3418-3427 10 p.

Research output: Contribution to journalArticlepeer-review

Research News

Two college students work with a professor while writing on a white board in a classroom.

Physics faculty publishes article in Nature family of journals

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photo from article Augusta University researcher named to 2023 Class of Fellows for the National Academy of Inventors

Augusta University researcher named to 2023 Class of Fellows for the National Academy of Inventors

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Augusta University researcher awarded Bill & Melinda Gates Foundation grant for disease detection research

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The College of Science and Mathematics provides students with strong foundations in the sciences as well as preparation for careers, citizenship, and a life-long love of learning. We are committed to providing experiences promoting scientific inquiry and discovery and dedicated to creating opportunities for intellectual growth and community involvement.