Alvin V .Terry, Jr., PhD
Investigates role of cholinergic systems in memory function, and how it is altered by diseases like schizophrenia and Alzheimer's Disease as well as toxins that are found in the environment such as organophosphate insecticides.
Scott A. Barman, PhD, FAHA
Investigates signal transduction mechanisms, mostly associated with Galectin-3 and Nox4 which is involved in Pulmonary Hypertension (PH).
Clare M. Bergson, PhD
Studies vesicle trafficking of neuronal proteins that are critical for brain development, and that are implicated in psychiatric and neurodegenerative disorders. Methods include live imaging of protein dynamics and interactions using neurons in culture and brain tissue.
R. William Caldwell, PhD
Studies role of availability of L-arginine for NOS in the cardiovascular dysfunctions in diabetes, hypertension, obesity and other diseases involving oxidative stress and inflammation. The group investigates the involvement of altered arginase expression and activity.
Gabor Csanyi, PhD
Our lab focuses on macrophage biology in atherosclerosis.
Tohru Fukai, MD, PhD, FAHA
Our lab focuses on oxidative stress and copper transporters in vascular metabolic disease.
David J. Fulton, PhD
Our lab focuses on the role of endothelium and reactive oxygen and nitrogen species in cardiovascular disease.
John A. Johnson, PhD
Investigates regulation of protein kinase C isozymes in cardiac mitochondrial dysfunction and ischemia /reperfusion (heart attack) injury. In addition to biochemical and proteomic analyses the lab utilizes a variety of cellular and subcellular peptide delivery tools in cell, whole heart and in vivo models of myocardial infarction.
Nevin A. Lambert, PhD
Investigates structure and function of G-protein-coupled receptor (GPCR) signaling complexes. His work uses biophysical methods such as resonance energy transfer and confocal imaging in living cells to investigate receptor quaternary structure and receptor-G protein coupling.
Rudolf Lucas, PhD
Our lab focuses on novel therapies for pulmonary edema.
Brian Muntean, PhD
Studies the rules and mechanisms governing information transfer between neurons, which are essential processes to provide instructions for locomotion and motor coordination. Research utilizes CRISPR/Cas9 gene editing tools in tandem with optical imaging strategies to interrogate the molecular architecture underlying neuronal signal decoding logic.
Raghavan P. Raju, PhD
Investigates molecular basis of organ function changes following injury and the influence of aging using a multidisciplinary approach. His research is currently focused on mitochondrial alterations and immune regulation following hemorrhagic shock towards identification of molecular mechanisms and therapeutic targets.
R. Daniel Rudic, PhD
Studies regulation of the cardiovascular system by intrinsic daily oscillations/rhythms (a circadian rhythm). Examines gene transcription factors Bmal1 and Clock as the molecular basis of these rhythmic patterns and vascular dysfunction.
Huabo Su, PhD
Our lab focuses on protein quality control in cardiac disease.
Yunchao Su, MD, PhD
Investigates the regulatory mechanisms of pulmonary circulation and lung injury and repair. The focus is on three areas: protein-protein interaction in lung endothelial signaling, calpain in hypoxic pulmonary vascular remodeling and angiogenesis, and lung injury and repair in tobacco smoke exposure.
Sangeetha Sukumari-Ramesh, PhD
Our studies focus on the identification and characterization of molecular targets of brain injury after intracerebral hemorrhage, a fatal stroke subtype employing both genetic and pharmacological approaches.
Almira Vazdarjanova, PhD
Uses a multilevel approach to investigate forebrain networks involved in encoding and consolidating of memories for emotional events in models of anxiety and impaired cognitive flexibility with special focus on individual differences. The lab has created an animal model of susceptibility for developing Post-Traumatic Stress Disorder.
Nicole Winston, Pharm.D
Dr. Nicole R. Winston is a Medical Educator and Assistant Professor with an appointment in the Department of Pharmacology and Toxicology. She specializes in teaching clinical therapeutics to Phase 2 and Phase 3 Medical Students. She teaches specific areas of Pharmacology to the 3rd and 4th year medical students through pharmacology special elective courses. She also teaches specific areas of Pharmacology to the Pharmacology and Toxicology graduate students using collaborative and team based learning initiatives. She is continuously researching techniques to help improve student learning.
Guangyu Wu, PhD
Studies G protein-coupled receptor (GPCRs) trafficking, particularly anterograde transport of nascent receptors to the functional destinations en route from the endoplasmic reticulum and the Golgi apparatus. Also investigates the role of G protein-mediated signaling in cancer biology.
Jiliang Zhou, PhD
His research focuses on smooth muscle biology. In particular, he examines the transcriptional control of vascular smooth muscle differentiation and phenotypic modulation. These studies are central to the management of vascular disease.