Denisha Spires

Other Faculty

Denisha Spires

Other Faculty

Academic Appointment(s)

Medical College of Georgia
Department of Physiology

  • DESPIRES@augusta.edu
  • (706) 721-8103
  • CA 3091

Education

  • Ph.D., Physiology, General Medical College of Wisconsin, 2020

  • BS, Biology/Biological Sciences, G Tougaloo College, 2015

Teaching Interests

Teaching interest align with renal physiology and physiology in general.

Scholarship

Selected Recent Publications

  • Male and Female Rats Display Divergent Renal Mitochondrial Bioenergetics in Aging, 2025
    Journal Article, Academic Journal
  • Atrial Natriuretic peptide deficiency in hypertensive pregnant rats induces adverse cardiac remodeling, fetal outcomes and maternal vascular dysfunction, 2025
    Journal Article, Academic Journal
  • Chronic Histamine-N-Methyltransferase Inhibition Attenuates Blood Pressure Development in Dahl SS Rats, 2025
    Journal Article, Academic Journal
  • Intracellular Ca 2+ Levels and Mitochondrial Bioenergetics in Proximal Tubule Cells Are Affected by Polyamines, 2025
    Journal Article, Academic Journal
  • Role of ANP in the Renal Proximal Tubule Mitochondrial Function in Type 1 DKD, 2025
    Journal Article, Academic Journal

Research Interests

My research background is in the pathophysiology of type 1 and type 2 diabetic nephropathy in relation to endothelin 1, podocyte calcium flux through the Transient Receptor Potential Cation Channel 6, and sex-based differences in the progression/severity. Currently, my research centers on the atrial natriuretic peptide (ANP) and mitochondrial oxidative stress in diabetic kidney disease.