Dhandapani Lab

Dhandapani

Publications

 

 

Publication
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Determinants of Outcome After Endovascular Middle Cerebral Artery Occlusion in Rats in the SPAN Trial

Jin, X., Morais, A., Imai, T., Lamb, J., Nagarkatti, K., Boisserand, L., Beatty, H. E., Sansing, L. H., Khan, M. B., Dhandapani, K., Kamat, P., Hess, D. C., Patel, R. B., Kumskova, M., Chauhan, A. K., McCullough, L. D., Aronowski, J., Leira, E. C., Shi, Y. & Avery, B. D. & 3 others, Koehler, R. C., Lyden, P. D. & Ayata, C., Sep 2025, In: Stroke. 56, 9, p. 2734-2747 14 p.

Research output: Contribution to journal › Article › peer-review

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Multicenter SPAN Trial of Fasudil in Ischemic Stroke

SPAN Investigators, Aug 1 2025, In: Stroke. 56, 8, p. 2306-2317 12 p.

Research output: Contribution to journal › Article › peer-review

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Time Dimension Influences Severity of Stroke and Heightened Immune Response in Mice

Kamat, P. K., Khan, M. B., Siddiqui, S., Williams, D., da Silva Lopes Salles, E., Naeini, S. E., Arbab, A. S., Rudic, D. R., Baban, B., Dhandapani, K. M. & Hess, D. C., Apr 2025, In: Translational Stroke Research. 16, 2, p. 421-437 17 p., e571.

Research output: Contribution to journal › Article › peer-review

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Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial

Patel, R. B., Kumskova, M., Kodali, H., Budnik, I., Kuznetsov, V., Jain, A., Jha, A., Thedens, D., Dhanesha, N., Sutariya, B., Nagarkatti, K. A., Lamb, J., Kamat, P., Shi, Y., Avery, B., Imai, T., Jin, X., Chauhan, A., Boisserand, L. S. B. & Khan, M. B. & 14 others, Dhandapani, K., Sanganahalli, B. G., Sansing, L. H., Hess, D. C., Koehler, R. C., McCullough, L. D., Aronowski, J., Ayata, C., Diniz, M. A., Lyden, P. D., Planas, A. M., Chamorro, A., Chauhan, A. K. & Leira, E. C., Apr 1 2025, In: Stroke. 56, 4, p. 965-973 9 p.

Research output: Contribution to journal › Article › peer-review

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Time of day dependent reduction in stroke infarct volume by the Reverb agonist SR9009 in mice

Kamat, P. K., Khan, M. B., Siddiqui, S., Hattaway, T. G., Anas, A., Rudic, R. D., Baban, B., Dhandapani, K. M. & Hess, D. C., Feb 2025, In: Experimental Neurology. 384, 115067.

Research output: Contribution to journal › Article › peer-review

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Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke

Alptekin, A., Khan, M. B., Parvin, M., Chowdhury, H., Kashif, S., Selina, F. A., Bushra, A., Kelleher, J., Ghosh, S., Williams, D., Blumling, E., Ara, R., Bosomtwi, A., Frank, J. A., Dhandapani, K. M. & Arbab, A. S., 2025, In: Frontiers in Neurology. 16, p. 1543133

Research output: Contribution to journal › Article › peer-review

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Optimization of seizure prevention by cannabidiol (CBD)

Bhandari, B., Naeini, S. E., Rezaee, S., Rogers, H. M., Khodadadi, H., Bosomtwi, A., Seyyedi, M., Mackinnon, N. J., Dhandapani, K. M., Salles, É. L., Hess, D. C., Yu, J. C., Moore-Hill, D., Vale, F. L., Wang, L. P. & Baban, B., Jan 1 2025, In: Translational Neuroscience. 16, 1, 20220362.

Research output: Contribution to journal › Article › peer-review

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Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke

Alptekin, A., Khan, M. B., Parvin, M., Chowdhury, H., Kashif, S., Selina, F. A., Bushra, A., Kelleher, J., Ghosh, S., Williams, D., Blumling, E., Ara, R., Bosomtwi, A., Frank, J. A., Dhandapani, K. M. & Arbab, A. S., 2025, In: Frontiers in Neurology. 16, 1543133.

Research output: Contribution to journal › Article › peer-review

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Boosting Acetylcholine Signaling by Cannabidiol in a Murine Model of Alzheimer’s Disease

Khodadadi, H., Salles, É. L., Naeini, S. E., Bhandari, B., Rogers, H. M., Gouron, J., Meeks, W., Terry, A. V., Pillai, A., Yu, J. C., Morgan, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M., Wang, L. P. & Baban, B., Nov 2024, In: International journal of molecular sciences. 25, 21, 11764.

Research output: Contribution to journal › Article › peer-review

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Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial

Morais, A., Imai, T., Jin, X., Locascio, J. J., Boisserand, L., Herman, A. L., Chauhan, A., Lamb, J., Nagarkatti, K., Diniz, M. A., Kumskova, M., Dhanesha, N., Kamat, P. K., Khan, M. B., Dhandapani, K. M., Patel, R. B., Sutariya, B., Shi, Y., van Leyen, K. & Kimberly, W. T. & 8 others, Hess, D. C., Aronowski, J., Leira, E. C., Koehler, R. C., Chauhan, A. K., Sansing, L. H., Lyden, P. D. & Ayata, C., Aug 16 2024, In: Circulation research. 135, 5, p. 575-592 18 p.

Research output: Contribution to journal › Article › peer-review

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Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma

Wang, L. P., Chagas, P. S., Salles, É. L., Naeini, S. E., Gouron, J., Rogers, H. M., Khodadadi, H., Bhandari, B., Alptekin, A., Qin, X., Vaibhav, K., Costigliola, V., Hess, D. C., Dhandapani, K. M., Arbab, A. S., Rutkowski, M., Yu, J. C. & Baban, B., Jun 2024, In: Medical Oncology. 41, 6, 140.

Research output: Contribution to journal › Article › peer-review

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Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment

Khodadadi, H., Salles, É. L., Alptekin, A., Mehrabian, D., Rutkowski, M., Arbab, A. S., Yeudall, W. A., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., Oct 1 2023, In: Cannabis and Cannabinoid Research. 8, 5, p. 824-834 11 p.

Research output: Contribution to journal › Article › peer-review

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A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke

Lyden, P. D., Diniz, M. A., Bosetti, F., Lamb, J., Nagarkatti, K. A., Rogatko, A., Kim, S., Cabeen, R. P., Koenig, J. I., Akhter, K., Arbab, A. S., Avery, B. D., Beatty, H. E., Bibic, A., Cao, S., Boisserand, L. S. B., Chamorro, A., Chauhan, A., Diaz-Perez, S. & Dhandapani, K. & 29 others, Dhanesha, N., Goh, A., Herman, A. L., Hyder, F., Imai, T., Johnson, C. W., Khan, M. B., Kamat, P., Karuppagounder, S. S., Kumskova, M., Mihailovic, J. M., Mandeville, J. B., Morais, A., Patel, R. B., Sanganahalli, B. G., Smith, C., Shi, Y., Sutariya, B., Thedens, D., Qin, T., Velazquez, S. E., Aronowski, J., Ayata, C., Chauhan, A. K., Leira, E. C., Hess, D. C., Koehler, R. C., McCullough, L. D. & Sansing, L. H., Sep 20 2023, In: Science Translational Medicine. 15, 714, eadg8656.

Research output: Contribution to journal › Article › peer-review

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Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation

Jarrahi, A., Khodadadi, H., Moore, N. S., Lu, Y., Awad, M. E., Salles, E. L., Vaibhav, K., Baban, B. & Dhandapani, K. M., Sep 2023, In: Journal of Thrombosis and Haemostasis. 21, 9, p. 2473-2484 12 p.

Research output: Contribution to journal › Article › peer-review

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Inflammaging, cellular senescence, and cognitive aging after traumatic brain injury

Lu, Y., Jarrahi, A., Moore, N., Bartoli, M., Brann, D. W., Baban, B. & Dhandapani, K. M., May 2023, In: Neurobiology of Disease. 180, 106090.

Research output: Contribution to journal › Article › peer-review

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Altered endocannabinoid metabolism compromises the brain-CSF barrier and exacerbates chronic deficits after traumatic brain injury in mice

Ahluwalia, M., Mcmichael, H., Kumar, M., Espinosa, M. P., Bosomtwi, A., Lu, Y., Khodadadi, H., Jarrahi, A., Khan, M. B., Hess, D. C., Rahimi, S. Y., Vender, J. R., Vale, F. L., Braun, M., Baban, B., Dhandapani, K. M. & Vaibhav, K., Mar 2023, In: Experimental Neurology. 361, 114320.

Research output: Contribution to journal › Article › peer-review

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Senolytic therapy is neuroprotective and improves functional outcome long-term after traumatic brain injury in mice

Wang, J., Lu, Y., Carr, C., Dhandapani, K. M. & Brann, D. W., 2023, In: Frontiers in Neuroscience. 17, 1227705.

Research output: Contribution to journal › Article › peer-review

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The time dimension to stroke: Circadian effects on stroke outcomes and mechanisms

Kamat, P. K., Khan, M. B., Smith, C., Siddiqui, S., Baban, B., Dhandapani, K. & Hess, D. C., Jan 2023, In: Neurochemistry International. 162, 105457.

Research output: Contribution to journal › Article › peer-review

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Trigeminal Neuralgia Treatment Outcomes Following Gamma Knife Stereotactic Radiosurgery

Jarrahi, A., Cantrell, R., Norris, C., Dhandapani, K., Barrett, J. & Vender, J., Dec 2022, In: International Journal of Translational Medicine. 2, 4, p. 543-554 12 p.

Research output: Contribution to journal › Article › peer-review

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Pilot Study of Remote Ischemic Conditioning in Acute Spontaneous Intracerebral Hemorrhage

Jarrahi, A., Shah, M., Ahluwalia, M., Khodadadi, H., Vaibhav, K., Bruno, A., Baban, B., Hess, D. C., Dhandapani, K. M. & Vender, J. R., May 12 2022, In: Frontiers in Neuroscience. 16, 791035.

Research output: Contribution to journal › Article › peer-review

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Regulation and Role of Neuron-Derived Hemoglobin in the Mouse Hippocampus

Lu, Y., Wang, J., Tang, F., Pratap, U. P., Sareddy, G. R., Dhandapani, K. M., Capuano, A., Arvanitakis, Z., Vadlamudi, R. K. & Brann, D. W., May 2 2022, In: International journal of molecular sciences. 23, 10, 5360.

Research output: Contribution to journal › Article › peer-review

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The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results

Lyden, P. D., Bosetti, F., Diniz, M. A., Rogatko, A., Koenig, J. I., Lamb, J., Nagarkatti, K. A., Cabeen, R. P., Hess, D. C., Kamat, P. K., Khan, M. B., Wood, K., Dhandapani, K., Arbab, A. S., Leira, E. C., Chauhan, A. K., Dhanesha, N., Patel, R. B., Kumskova, M. & Thedens, D. & 23 others, Morais, A., Imai, T., Qin, T., Ayata, C., Boisserand, L. S. B., Herman, A. L., Beatty, H. E., Velazquez, S. E., Diaz-Perez, S., Sanganahalli, B. G., Mihailovic, J. M., Hyder, F., Sansing, L. H., Koehler, R. C., Lannon, S., Shi, Y., Karuppagounder, S. S., Bibic, A., Akhter, K., Aronowski, J., McCullough, L. D., Chauhan, A. & Goh, A., May 1 2022, In: Stroke. 53, 5, p. 1802-1812 11 p.

Research output: Contribution to journal › Article › peer-review

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A potential role for cannabichromene in modulating TRP channels during acute respiratory distress syndrome

Khodadadi, H., Salles, É. L., Shin, E., Jarrahi, A., Costigliola, V., Kumar, P., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., Dec 2021, In: Journal of Cannabis Research. 3, 1, 45.

Research output: Contribution to journal › Article › peer-review

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Inflammaging and Cannabinoids

Baban, B., Khodadadi, H., Salles, É. L., Costigliola, V., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Yu, J. C., Dec 2021, In: Ageing Research Reviews. 72, p. 101487 101487.

Research output: Contribution to journal › Article › peer-review

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Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages - A potential therapeutic approach

Ahluwalia, M., Kumar, M., Ahluwalia, P., Rahimi, S., Vender, J. R., Raju, R. P., Hess, D. C., Baban, B., Vale, F. L., Dhandapani, K. M. & Vaibhav, K., Nov 2021, In: Neurochemistry International. 150, 105192.

Research output: Contribution to journal › Article › peer-review

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Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia

Wang, J., Zhang, Q., Lu, Y., Dong, Y., Dhandapani, K. M., Brann, D. W. & Yu, R. K., Aug 2021, In: Journal of Neurochemistry. 158, 3, p. 737-752 16 p.

Research output: Contribution to journal › Article › peer-review

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Conditioning medicine for ischemic and hemorrhagic stroke

Hess, D. C., Khan, M. B., Kamat, P., Vaibhav, K., Dhandapani, K. M., Baban, B., Waller, J. L., Hoda, M. N., Blauenfeldt, R. A. & Andersen, G., Jun 2021, In: Conditioning medicine. 4, 3, p. 124-129 6 p.

Research output: Contribution to journal › Article › peer-review

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Pulsed Focal Ultrasound as a Non-Invasive Method to Deliver Exosomes in the Brain/Stroke

Alptekin, A., Khan, M. B., Ara, R., Rashid, M. H., Kong, F., Parvin, M., Frank, J. A., Chopra, R., Dhandapani, K. & Arbab, A. S., Jun 1 2021, In: Journal of Biomedical Nanotechnology. 17, 6, p. 1170-1183 14 p.

Research output: Contribution to journal › Article › peer-review

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AMPK induces regulatory innate lymphoid cells after traumatic brain injury

Baban, B., Braun, M., Khodadadi, H., Ward, A., Alverson, K., Malik, A., Nguyen, K., Nazarian, S., Hess, D. C., Forseen, S., Post, A. F., Vale, F. L., Vender, J. R., Nasrul Hoda, M., Akbari, O., Vaibhav, K. & Dhandapani, K. M., Jan 11 2021, In: JCI Insight. 6, 1, e126766.

Research output: Contribution to journal › Article › peer-review

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Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

Singleton, Q., Vaibhav, K., Braun, M., Patel, C., Khayrullin, A., Mendhe, B., Lee, B. R., Kolhe, R., Kaiser, H., Awad, M. E., Fariyike, T., Elsayed, R., Elsalanty, M. E., Isales, C. M., Liu, Y., Hamrick, M. W., Dhandapani, K. M. & Fulzele, S., Jan 2021, In: Fuel Cells. 8, 1, 63.

Research output: Contribution to journal › Article › peer-review

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Cannabidiol ameliorates cognitive function via regulation of IL-33 and TREM2 upregulation in a murine model of Alzheimer's Disease

Khodadadi, H., Salles, É. L., Jarrahi, A., Costigliola, V., Khan, M. B., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., 2021, In: Journal of Alzheimer's Disease. 80, 3, p. 973-977 5 p.

Research output: Contribution to journal › Article › peer-review

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Infections of the lung: a predictive, preventive and personalized perspective through the lens of evolution, the emergence of SARS-CoV-2 and its pathogenesis

Ahluwalia, P., Ahluwalia, M., Vaibhav, K., Mondal, A., Sahajpal, N., Islam, S., Fulzele, S., Kota, V., Dhandapani, K., Baban, B., Rojiani, A. M. & Kolhe, R., Dec 2020, In: EPMA Journal. 11, 4, p. 581-601 21 p.

Research output: Contribution to journal › Review article › peer-review

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Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome

Salles, É. L., Khodadadi, H., Jarrahi, A., Ahluwalia, M., Paffaro, V. A., Costigliola, V., Yu, J. C., Hess, D. C., Dhandapani, K. M. & Baban, B., Nov 2020, In: Journal of Cellular and Molecular Medicine. 24, 21, p. 12869-12872 4 p.

Research output: Contribution to journal › Article › peer-review

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Revisiting traumatic brain injury: From molecular mechanisms to therapeutic interventions

Jarrahi, A., Braun, M., Ahluwalia, M., Gupta, R. V., Wilson, M., Munie, S., Ahluwalia, P., Vender, J. R., Vale, F. L., Dhandapani, K. M. & Vaibhav, K., Oct 2020, In: Biomedicines. 8, 10, p. 1-42 42 p., 389.

Research output: Contribution to journal › Review article › peer-review

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Neurological consequences of COVID-19: What have we learned and where do we go from here?

Jarrahi, A., Ahluwalia, M., Khodadadi, H., Da Silva Lopes Salles, E., Kolhe, R., Hess, D. C., Vale, F., Kumar, M., Baban, B., Vaibhav, K. & Dhandapani, K. M., Sep 30 2020, In: Journal of Neuroinflammation. 17, 1, 286.

Research output: Contribution to journal › Review article › peer-review

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Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M. & Baban, B., Sep 1 2020, In: Cannabis and Cannabinoid Research. 5, 3, p. 197-201 5 p.

Research output: Contribution to journal › Article › peer-review

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Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies

Reddy, V., Grogan, D., Ahluwalia, M., Salles, É. L., Ahluwalia, P., Khodadadi, H., Alverson, K., Nguyen, A., Raju, S. P., Gaur, P., Braun, M., Vale, F. L., Costigliola, V., Dhandapani, K., Baban, B. & Vaibhav, K., Jun 1 2020, In: EPMA Journal. 11, 2, p. 217-250 34 p.

Research output: Contribution to journal › Review article › peer-review

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Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N. & Baban, B. & 1 others, Dhandapani, K. M., May 2020, In: Science Advances. 6, 22, p. eaax8847 EAAX8847.

Research output: Contribution to journal › Article › peer-review

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Honey: A Sweet Way to Health

Ahluwalia, M., Ahluwalia, P., Dhandapani, K. M. & Vaibhav, K., Jan 1 2020, Therapeutic Applications of Honey and its Phytochemicals: Vol.1. Springer Singapore, Vol. 1. p. 53-80 28 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C. D., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, M. N. & Stice, S. L., Oct 1 2018, In: Translational Stroke Research. 9, 5, p. 530-539 10 p.

Research output: Contribution to journal › Article › peer-review

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