News & Events

Student Awards

Congratulations to our students for all of their hard work!

Phi Kappa Phi Conference

Sneha Cauhan received "Best Presentation Oral Award" in the Arsenal A Oral Symposium session.

Graduate Research Day 2021

Rebekah Robinson received the ThermoFisher/Phi Kappa Phi Excellence in Research Award.
Marissa Seamon received the Graduate School Award for Excellence in Research.
Yanyan Xu received the Award for Excellence in Research – Genomic Medicine.

Added April 2021

New approach emerges to better classify, treat brain tumors

Paul Tran

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

Proteins could be source for new blood test for cervical cancer, better therapies

Dr. Sharad Purohit

For cervical cancer patients, for instance, the therapy could include quercetin, a plant-derived flavonol, and vitamin C.

Gene signature found for poor response to standard chemotherapy in rare uterine cancer

Lynn Tran

Women who don’t survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

Augusta University cancer therapy research turning to COVID-19

Dr. Jin-Xiong She

After working to try and create therapies that specifically target cancer cells, Dr. Jin-Xiong She is hoping to use that same approach to create a new therapy for COVID-19.

Tran receives scholarship honoring women in higher education

Lynn

CONGRATULATIONS TO LYNN TRAN

Great News! Lynn Tran, MD/PhD student of CBGM, has received the 2020 Louise McBee Scholarship sponsored by the Georgia Association for Women in Higher Education (GAWHE).

Congratulations Lynn!

Guest Speaker: Minglu Gao, B.E.

Friday, May 25th, 2018

guest speaker Minglu Gao

Seminar Title:
Molecular exploration of fungal beta-lactamases and antagonisms between two maize endophytes, Fusarium verticillioides and Sarocladium zeae

Fusarium verticillioides (Fv) is a prevalent seed-borne maize endophyte capable of causing severe kernel rot and fumonisin mycotoxin contamination. Within maize kernels, Fv is primarily confined to the pedicel, while another co-occurring seed-borne fungal endophyte, Sarocladium zeae (Sz), is generally isolated in the endosperm and embryo. In vitro competition assays have indicated Sz can inhibit the growth of Fv. The two lactam-containing antibiotics produced by Sz, named pyrrocidine A and B, are associated with this inhibition of Fv. To explore the mechanism of antagonism, RNA-seq experiments were conducted by challenging the Fv with pyrrocidine B at subinhibitory concentrations. Among the most differentially expressed genes was FVEG_11089 (up-regulated 470-fold) that codes for an ABC transporter. Deletion of FVEG_11089 caused increased sensitivity of Fv to pyrrocidine B. The expression of FVEG_11089 is independent of its adjacent and similarly-induced transcription factor. Additionally, deletion of a PB-induced zinc-binding dehydrogenase gene in Fv led to >10-fold increase in fumonisin production compared to wild type. Hence, we theorize that FVEG_11089 functions in pyrrocidine B resistance by transporting the antibiotic out of the Fv cells. Exposure to pyrrocidine B may suppress fumonisin production and affect the pathogenicity of Fv. Further exploration of the antifungal resistance mechanisms addresses the overall competitive relationships of the two maize seed endophytes colonizing the same ecological niche and how they cope with xenobiotic challenges.

Graduate Research Day Awards

Friday, March 23^th, 2018
Augusta University

Lynn Tran

Lynn KH Tran, recipient of the 2018 Graduate Day Research Award in Genomic Medicine.

McIndoe honored with Georgia Bio Award

February 14, 2018

McIndoe

Dr. Richard McIndoe is one of the recipients of the 2018 Life Sciences Health Impact Awards from Georgia Bio. McIndoe and the MCG Center for Biotechnology and Genomic Medicine will receive the group's Deal of the Year Award.

New technology enables identification of biomarkers for a wide range of diseases

February 12, 2018

She, Purohit and Sharma

'Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.'

Graduate Research Day Awards Banquet

Tuesday, March 28^th, 2017
At the Kroc Center, Augusta University

It was at the Graduate Research Day Awards Banquet

At the Graduate Research Day awards banquet, CBGM graduate students were honored for their recent successes. Robert Schleifer (left), a 5th year PhD student in the laboratory of Dr. Jin-Xiong She, was recognized for being a semi-finalist in Augusta University's inaugural 3MT competition. Paul Tran (middle left), a Graduate Year 1 M.D./Ph.D. student in Dr. She's lab, received an award for his Graduate Research Day poster as the recipient of the Award for Excellence in Research in Genomic Medicine. Also pictured are fellow graduate student Lynn Tran (middle right) and their mentor, Dr. She (right).

2016

Augusta University is researching a new drug that might help with diabetes-related blindness

Tuesday, December 27, 2016

'Dr. Shruti Sharma of the Center for Biotechnology and Genomic Medicine has a $1.5 million grant from the National Eye Institute to look at basic research into blocking inflammation among epithelial cells in light-sensing retina in the eye, Sharma is looking at a well-known agent in inflammation called interleukin-6 that can affect those cells even though they lack the receptor normally needed for such interaction, an effect called trans-signaling.'

Therapy could be guided 'missile' against cancer

Monday, August 1, 2016

She & Liu

'Using a double-targeted vehicle to home in on prostate cancer cells provides a highly targeted attack against interlocking mechanisms of survival to induce cell death and shrink tumors,'

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