Professor
Department of Neuroscience & Regenerative Medicine
Mailing Address:
Department of Neuroscience & Regenerative Medicine
1120 15th Street, Rm. CA4002
Medical College of Georgia Augusta University
Augusta, GA 30912
Phone: 706-721-9399
E-mail: dblake@augusta.edu
Education:
1990 Duke University, BSE, Biomedical Engineering
1995 Johns Hopkins School of Medicine, PhD
Training:
1996-2000 UCSF, Keck Center, Postdoctoral Scholar
2001-2004 UCSF, Keck Center, Asst Research Scientist
2004-5 UCSF, Keck Center, Adjunct Assistant Professor
Research interests:
My work has focused on interactions between electrophysiology and behavior. Earlier work predominantly investigated sensory systems particularly the senses of touch and hearing, at the cortical level. Later work has branched out to investigate mechanisms of executive function including working memory and sustained attention. Current work is focused on the use of deep brain stimulation of the cholinergic forebrain to alter cognition in mice, monkeys, and humans.
Current projects:
1) Deep brain stimulation of the cholinergic forebrain in aged animals.
2) Impacts of cholinergic deep brain stimulation on acetylcholine levels, brain
blood flow, and amyloid pathways.
3) Deep brain stimulation human clinical trials.
Lab members:
Our work is highly collaborative.
Jacob Kumro - MD/PhD Student
Kendyl Pennington - Technician
Collaborations at AU:
Alvin Terry, PhD
Marc Plagenhoef, Res. Asst.
Sergei Kirov, PhD
Jeremy Sword, PhD
Anil Pillai, PhD
Collaboration at Wake Forest:
Christos Constantinidis, PhD
Xuelian Qi, PhD
Selected publications:
