Dr. Kumar Vaibhav’s lab is dedicated to explore the mechanism behind immune cells activation post-brain injury.

They have found that immune cells, especially macrophages, T cells and innate lymphoid cells, can be polarized to pro-inflammatory states after injury, which leads to long-term chronic injury and neurological deficits. The lab further reported that modulation of cannabinoid system helps immensely to maintain the equilibrium between different polarized states of immune cells and thus, expediting the recovery from injury. However, PI emphasizes that there is a lot more to explore related to brain injury and role of cannabinoid system in homeostasis.

The lab is funded through several NIH extramural awards and is actively involved in studies related to cannabinoid and non-cannabinoid system in Traumatic brain injury (TBI) and Intracerebral hemorrhages (ICH).



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