Santhakumar Manicassamy


Santhakumar Manicassamy


Academic Appointment(s)

Medical College of Georgia
Department of Medicine: Infectious Disease

Medical College of Georgia
Department of Georgia Cancer Center

Medical College of Georgia
Department of Biochemistry and Molecular Biology

The Graduate School


Dr. Santhakumar Manicassamy is an Associate Professor of Georgia Cancer Center at Augusta University. He received his undergraduate and a graduate degree from Pondicherry University, India, and his Ph.D. from the University of Illinois, Chicago. He then did his post-doctoral work at the Emory Vaccine Center, Emory University, Atlanta. Dr. Manicassamy’s work focuses on understanding the molecular mechanisms by which innate immune cells shape adaptive immune responses and harnessing such mechanisms to treat immune cell-mediated inflammatory diseases and design novel vaccines against pathogens and tumors.

  • (706) 721-7902
  • CN 4143


  • Ph.D., MicroBio Sci and Immunology University of Illinois Chicago, 2006

Courses Taught Most Recent Academic Year

  • BCMB 8201

    Cur Topics & Tech in MB
  • BIOM 8033

    Integrated Systems Biol
  • BIOM 8240

    Intro to Imm/Inf Disease


Selected Recent Publications

  • Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation., 2021
    Journal Article, Academic Journal
  • RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy., 2021
    Journal Article, Academic Journal
  • Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages., 2021
    Journal Article, Academic Journal
  • Mouse Models of Colitis-Associated Colon Cancer., 2021
    Journal Article, Academic Journal
  • The Wnt-β-Catenin-IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota., 2020
    Journal Article, Academic Journal

Department Service

  • Flow Core Advisory Committee Agend 2021

    Role: Committee Member
  • IMSR Advisory Committee 2020

    Role: Committee Member

University Service

  • IACUC committee 2022

    Role: Committee Member
  • Graduate Students Dissertation Committees 2022

    Role: Committee Member

Professional Service

  • NIH Study section panel reviewer - 2022

    Role: Reviewer, Grant Proposal
  • Associate Editor for Frontiers in Immunology - 2022

  • Journal reviewer - 2022

    Role: Reviewer, Journal Article
  • UK Research and Innovation (UKRI) Medical Research Council (2021) - 2021

    Role: Reviewer, Ad Hoc Reviewer