Mykola Mamenko

Associate Professor

Mykola Mamenko

Associate Professor

Academic Appointment(s)

Medical College of Georgia
Department of Physiology

Administration
Department of The Graduate School

Education

  • Ph.D., Biophysics Taras Shevchenko National Univ, 2010

Awards & Honors

  • Epithelial Transport Group Meritorious Research Award The American Physiological Society, 2017

  • Renal Section Research Recognition Award The American Physiological Society, 2017

  • Dean’s Excellence in Research Award The University of Texas Medical School, 2015

  • Renal Section Postdoctoral Excellence in Research Award The American Physiological Society, 2015

  • Young Investigator Award The Society of Experimental Biology and Medicine, 2015

Courses Taught Most Recent Academic Year

  • PSIO 9210

    Invest of a Problem
  • PSIO 6110

    Medical Physio 1
  • VBIO 8010

    Methods in Cardiovascular Rese
  • PSIO 6710

    Pathophys 1
  • PSIO 9300

    Research
  • BIOM 8130

    Scientific Grant Writing
  • PSIO 8340

    Advanced Study Physiology
  • CURS 2990

    Undergrad Research I
  • PSIO 7210

    Advanced Renal Phys
  • BIOM 8033

    Integrated Systems Biol
  • MEDI 5005

    Integrative Science
  • PSIO 7410

    Research

Teaching Interests

My professional aspiration is to promote the growth and development of trainees, so that they are successful in the academic and biomedical fields, or outside of those areas (industry, scientific writing etc.). My teaching strategy is based on the following principles: 1) encourage problem-solving thinking and application of the acquired knowledge; 2) emphasize and foster communication skills, they are vital to succeed in any modern career; 3) maintain realistic expectations about the educational and career goals; 4) stress the critical importance of professional ethics and rigor; 5) lead by example and avoid the “one size fits all” approach. I have been delivering didactic lectures to the graduate and master’s students within the curricula of the following courses: Scientific Communication (BIOM 8012), Integrated Systems Biology (BIOM 8033), Methodology in Cardiovascular Research (VBIO 8010), Medical Physiology I (PSIO 6110), Pathophysiology (PSIO 6710), Advanced Renal Physiology (PSIO 7210), Medical Renal Physiology (PSIO 8390). I have developed the curriculum and served as the main instructor for the Current Trends in Physiology: Mineralocorticoid and Progesterone Signaling – Evolution, Function, Interaction (PSIO 8350) and Advanced Study of Physiology: Animal Models of Kidney Disease (PSIO 8340) courses.

Scholarship

Selected Recent Publications

  • Aldosterone Antagonism Is More Effective at Reducing Blood Pressure and Excessive Renal ENaC Activity in AngII-Infused Female Rats Than in Males, 2023
    Journal Article, Academic Journal
  • TRPV4 functional status in cystic cells regulates cystogenesis in autosomal recessive polycystic kidney disease during variations in dietary potassium., 2023
    Journal Article, Academic Journal
  • Practical notes on popular statistical tests in renal physiology, 2022
    Journal Article, Academic Journal
  • Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice., 2020
    Journal Article, Academic Journal
  • TRPC3 determines osmosensitive [Ca2+]i signaling in the collecting duct and contributes to urinary concentration., 2019
    Journal Article, Academic Journal

Research Interests

My research program investigates how specific mechanisms responsible for water and electrolyte transport in the kidney are affected in pathology and seeks to translate the obtained mechanistic evidence to develop new or update the existing therapeutic strategies. The main lines of inquiry pursued in the lab explore sex differences in aldosterone-dependent renal sodium reabsorption that are critical for chronic blood pressure control, delineate molecular determinants of lithium toxicity in the kidney, examine renal mechanisms contributing to the development of hyperkalemia in the setting of chronic kidney disease and aim to understand long-term impact of hyperkalemia on renal and cardiovascular outcomes. The methodological arsenal at our disposal allows exploring our hypotheses at the cellular, tissue and systemic levels to generate preclinical evidence of high translational value.

Department Service

  • Seminar Series 2018 - 2019

    Role: Committee Chair
  • Symposium: "Immune system and inflammation as modulators of physiological function in health and disease" 2018

    Role: Other

University Service

  • MCG Graduate Student Research Day 2018

    Role: Other

Professional Service

  • American Heart Association, Cardiorenal – Basic Science 1 Committee 2018 - Present

    Role: Reviewer
  • American Heart Association, Council on the Kidney in Cardiovascular Disease, Membership & Communications Committee 2018 - Present

    Role: Committee Member
  • Basic Research Forum for Emerging Kidney Scientists virtual session of “The chicken-and-egg of acute kidney injury: nephron damage vs. vascular congestion” 2020 - 2020

    Role: Other
  • American Physiological Society “Novel Regulators of Renal Tubular Transport” Session - 2019

    Role: Session Chair
  • American Physiological Society Abstract-driven Oral Session "Emerging Kidney Physiologists" - 2019

    Role: Session Chair