Kenneth Kwon

Scholarship

Selected Recent Publications

• Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis, 2024
  Journal Article, Academic Journal
• Mature microRNA-binding protein QKI suppresses extracellular microRNA let-7b release, 2024
  Journal Article, Academic Journal
• Quantitative analysis of radiosensitizing effect for magnetic hyperthermia-radiation combined therapy on prostate cancer cells, 2024
  Journal Article, Academic Journal
• Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair, 2023
  Journal Article, Academic Journal
• Extracellular vesicle microRNA in the kidney, 2023
  Journal Article, Academic Journal

Research Interests

Our laboratory is dedicated to investigating the role of small bioactive entities—such as exosomes, nanoparticles, and microRNAs—in the pathogenesis and resolution of organ injury. These small molecules and vesicles have emerged as potent mediators of intercellular communication, capable of propagating injury signals or modulating tissue responses. Our current research centers on two fundamental questions: first, how they control tissue damage in acute and chronic organ injury, and second, whether their inherent biological properties can be engineered to mitigate injury and promote repair. By elucidating the dualistic nature of these entities—as drivers of pathology and potential therapeutic agents—we aim to uncover novel molecular targets and intervention strategies for organ protection and recovery .